Product Information:

OsteoGen® Synthetic Bioactive Resorbable crystals and crystal clusters, ranging in size from 300 to 400μ, exhibit osteoconductive properties, high hydrophilicity, and resorbability. They are a synthetically-derived, non-ceramic form of hydroxylapatite, which is the primary mineral component of both bone and dental enamel. OsteoGen®, scientifically denoted as [Ca5(PO4)3(OH)], is utilized for augmenting and repairing periodontal and oral-maxillofacial bone defects.

OsteoGen® stands out as a highly crystalline and pure material, mirroring natural bone in its physiochemical attributes. It is devoid of α/β tricalcium phosphates, amorphous phases, or bone-inhibiting pyro-phosphates commonly found in ceramic hydroxyapatite (HA), which lacks the hydroxyl group.

Precise manufacturing techniques yield bone grafting crystals that form near-perfect clusters anchored to a single nucleus, sporting a relatively hexagonal shape. These clusters interlock to create enhanced porosity, forming a 360º lattice structure conducive to host cell proliferation and integration.

Functioning as an osteoconductive substance, OsteoGen® features highly porous crystalline clusters that serve as a slowly resorbing matrix, facilitating the infiltration of bone-forming cells and subsequent deposition of host bone tissue. Notably, OsteoGen® non-ceramic crystal clusters exhibit high hydrophilicity, enabling rapid absorption of medullary blood. This helps minimize migration or material loss, often addressed through the use of gauze to control excessive bleeding.

When assessed through x-ray diffraction, OsteoGen® surpasses ASTM standards and specifications. Upon initial placement in defect sites, OsteoGen® bone graft material appears radiolucent on dental x-rays. However, after four to six months, radiopacity develops, influenced by factors such as vascularity, the patient's age, and the quantity of product delivered. Numerous animal and clinical studies have demonstrated OsteoGen®'s effectiveness in controlling connective tissue migration.

Preparation is straightforward, and delivery can be easily accomplished using conventional instruments or a syringe, as the material maintains a sandy consistency.

Ensure thorough compaction of the product within the defect site.

OsteoGen's bioactive resorbable apatite closely emulates the structure of bone, facilitating bone regeneration during dental bone graft procedures. These calcium apatite bone-grafting crystals are hydrophilic, meaning they attract blood to initiate the regrowth process. Additionally, they possess bioactive and resorbable properties, allowing them to interact with the patient's cells and gradually break down into harmless components that can be assimilated by the body. This makes them exceptionally valuable for dental bone grafts. OsteoGen crystal clusters initially appear radiolucent on the day of placement but transition to radiopaque status within four to six months post-placement. This feature simplifies the assessment of bone growth, indicating the readiness for implant placement.